Kimata Lab 木全研究组

Posted on June 1st 2025 Our new review is now published: Mitotic signalling in progenitor cells: Integrating cell division with cell specificationTorcato Martins & Yuu Kimata https://doi.org/10.1016/j.ceb.2025.102542 This mini-review explores how cell cycle regulators (CCRs)—such as CDKs, Plk1, Aurora kinases, and APC/C—not only drive mitosis but also integrate cell division with fate decisions. We highlight […]

Posted on 2025/05/13 We are excited to share that our latest study, “Krüppel Regulates Cell Cycle Exit and Limits Adult Neurogenesis of Mushroom Body Neural Progenitors in Drosophila,” has been published as a Reviewed Preprint on eLife. This research uncovers the pivotal role of the transcription factor Krüppel (Kr) in promoting timely cell cycle exit […]

2025/04/11 We were honoured to host Professor Andrea Musacchio, a leading authority in the field of cell division and the spindle assembly checkpoint (SAC), at ShanghaiTech University. Professor Musacchio is the Director of the Department of Mechanistic Cell Biology at the Max Planck Institute of Molecular Physiology in Dortmund, Germany. His pioneering research has significantly […]

Posted: March 2025 We are excited to share that our latest work, titled “Krüppel Regulates Cell Cycle Exit and Limits Adult Neurogenesis of Mushroom Body Neural Progenitors in Drosophila”, is now available as a preprint on bioRxiv!Read it here In this study, we identify the conserved transcription factor Krüppel (Kr) as a key regulator that […]

Posted: January 2025 We are excited to welcome two new Master’s students, Xinyue Yu (Kate) and Yecheng Lei (Ray), who joined the Kimata Lab in January 2025. Kate graduated from China Pharmaceutical University and has joined the Drosophila team, where she will be investigating the role of cell cycle regulators in neurogenesis. Ray graduated from […]

Alexandra van Breemen (Alex), a medical student from Leiden University, Netherlands, joined the Kimata Lab through the 2024 ShanghaiTech Summer Lab Program (July 6–August 30). Her research focused on CDK1 phosphorylation in the EGFR-Ras-MAPK pathway using Drosophila models, contributing fresh perspectives to cell cycle regulation studies. With dual expertise in medicine and biomedical sciences, Alex demonstrated strong skills in molecular biology […]

In mid-July, our school hosted the annual summer camp, a key student recruitment event for our graduate program. This tradition has become an essential platform for connecting our school with prospective graduate students, enabling them to explore our research, faculty, environment, activities, and student life. This year’s summer camp saw around 200 promising candidates in […]

On May 10th 2023, our laboratory celebrated two outstanding achievements as Amanda and June successfully defended their theses. Amanda (Zhang Qian) has become the first PhD from our lab at ShanghaiTech. She impressed us with her work on the regulation of Dpp signalling by the cell cycle regulator APC/C-SnoN, and on the role of Spd2 […]

We are thrilled to share that our lab members recently attended the China Society of Cell Biology (CSCB) Meeting held in Suzhou from April 11th-14th, 2023.  This was not only a great opportunity for us to share our latest research findings, but also the first event we have been able to attend since the beginning […]

We are excited to share our recent paper published in EMBO Reports on the regulation of centrosome asymmetry in Drosophila neural stem cells. Centrosomes play a critical role in the development and physiology of animals, and our study sheds light on the role of ubiquitin-mediated proteolysis in the precise regulation of centriole duplication and beyond. […]